Welcome to DisSetSim
- Functional similarity between molecules results in similar phenotypes, such as diseases. Therefore, it is an effective way to reveal the function of molecules based on their induced diseases. However, the lack of a tool for obtaining the similarity score of pair-wise disease sets (SSDS) limits this types of application. Here, we introduce DisSetSim, an online system to solve this problem in this article. Five state-of-the-art methods involving Resnik’s method, Lin’s method, Wang’s method, PSB method, and SemFunSim method were implemented to measure the similarity score of pair-wise diseases (SSD) first. And then “pair-wise-best pairs-average” (PWBPA) method was implemented to calculated the SSDS.
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- Liang Cheng, et al. DisSetSim: an online system for calculating similarity between disease sets.